Clozapine

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Clozaril (Novartis); Denzapine (Merz); Entumin; Entumine; FazaClo; Klozapol; Leponex (Novartis); Lozapin; Sizopin; Zaponex (Teva)
  • INDICATIONS: Treatment-resistant schizophrenia
  • CLASS: Antipsychotic
  • HALF-LIFE: 4–12 hours

Contraindicated in patients with myeloproliferative disorders, uncontrolled epilepsy, paralytic ileus, or a history of clozapine-induced agranulocytosis or severe granulocytopenia.

AGRANULOCYTOSIS / SEIZURES / MYOCARDITIS / OTHER ADVERSE CARDIOVASCULAR AND RESPIRATORY EFFECTS

INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS


See full prescribing information for complete boxed warnings.

Our database has 140 adverse reactions for this drug across the following areas

Please login to see the rest of this drug profile


Not a subscriber? Click here to subscribe

SKIN
HAIR
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OTIC
OCULAR
OTHER


Page last updated 09/11/2017

Drug Eruption Mobile Site

Symbol key

Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric