Romidepsin
- TRADE NAME: Istodax (Celgene)
- INDICATIONS: Cutaneous T-cell lymphoma (CTCL)
- CLASS: Histone deacetylase (HDAC) inhibitor
- HALF-LIFE: 3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Atazanavir, Carbamazepine, Clarithromycin, Conivaptan, Coumadin derivatives, CYP3A4 inhibitors and inducers, Darunavir, Delavirdine, Dexamethasone, Efavirenz, Indinavir, Itraconazole, Ketoconazole, Nefazodone, Nelfinavir, Oxcarbazepine, Phenobarbital, Phenytoin, Rifabutin, Rifampin, Rifapentine, Ritonavir, Saquinavir, St John's Wort, Telithromycin, Voriconazole, Warfarin
PREGNANCY CATEGORY: D
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric