Gliclazide
- TRADE NAMES: Adionor; Diamicron (Servier); Diamicron MR (Servier); Diaprel
- INDICATIONS: Non-insulin dependent diabetes mellitus
- CLASS: Sulfonylurea
- HALF-LIFE: 10–12 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Beta andrenergic blocking agents, Chloramphenicol, Cimetidine, Clofibrate, coumarin derivatives, Disopyramide, MAO inhibitors, Miconazole, Phenylbutazone, salicylates, sulfonamides, Tetracycline
PREGNANCY CATEGORY: C
Gliclazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome
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SKIN.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric